Re: Standard of Care, nuchal translucency

From: ATB28@aol.com
Tue Feb 2 22:11:30 1999


In a message dated 2/2/1999 8:22:15 PM Pacific Standard Time, pdl@whidbey.net writes:

<< What is the feeling of this group? If you find yourself doing a scan > between 10 menstrual weeks and 14 menstrual weeks, could you be found
> wanting for not evaluating the nuchal translucency during that scan? >>

Lacking uniform guidelines for assessment of normal and abnormal values; consistency in training, evaluation, scan technique and reporting; ongoing quality assessment (all 3 advocated by Kypros Nicolaides' group before a program is initiated); and - most importantly - acknowledgement by ACOG that this represents a standard of contemporary obstetric practice, NT screening in the first trimester should certainly be considered investigational at present. It should be accomplished in centers under research protocol and patients evaluated should be informed of the current standard of care of screening for aneuploidy in the U.S., vis-a-vis multiple marker screening in the 2nd trimester.

At present, at least 2 prospective randomized U.S. trials are in the offing. Once completed, these should answer the questions about validity of screening for aneuploidy using NT and serum markers in the 1st trimester. Also at present, NT screening in the first trimester is NOT standard of practice in this country. Thus, one would *not* be found wanting for failing to offer an investigational service outside of study protocol.

Allan T. Bombard, MD Clinical Professor, Obstetrics & Gynecology and Women's Health Albert Einstein College of Medicine





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