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Re: MSAFP vs triple screen From: Samir Saidi (sam@saidi.prestel.co.uk) Wed Jul 9 14:47:19 1997 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: cy: "Online Live Discussion" Previous message: Todd Gastaldo: "OB-GYN-Listowner Geffrey Klein, MD: I discuss my obgyn posting "inspiration" publicly at the end of this post. Thank you for asking so courteously." Maybe in reply to: Danny Tucker: "MSAFP vs triple screen" Next in thread: Samir Saidi: "Re: MSAFP vs triple screen" Is it a good idea to have a blanket policy? If you screen all your patients (incl. <35) with double/triple testing, your false positive rate must increase (the 60% pick-up rate applies only to maternal age >35). That's fine if you think an amnio's no problem, as well as the anxiety of having the wait, especially if you then decline amnio. Conversely, how reassuring is a negative test in reality, with 40% false negatives? I'm all for triple testing in the right clinical situations, but there seems to be (over here at least) a tendency to say "have a blood test for down's" with little explanation of the significance and consequences. SO, what about fetal nuchal translucency? Current (last month) quoted figures I believe, based on Kypros Nicholaides formulae, are a sensitivity of 80% for Down's. No extra cost? - 12/40 scan for dating often performed anyway. And I think more reassuring for the patient. References available - I hope:) -- Sam Saidi, O&G trainee, University Hospital, Nottingham, UK Next message: cy: "Online Live Discussion" Previous message: Todd Gastaldo: "OB-GYN-Listowner Geffrey Klein, MD: I discuss my obgyn posting "inspiration" publicly at the end of this post. Thank you for asking so courteously." Maybe in reply to: Danny Tucker: "MSAFP vs triple screen" Next in thread: Samir Saidi: "Re: MSAFP vs triple screen"

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