Re: Breakthrough on Lupron

From: Laurie Lovely (llovely@med.unc.edu)
Sat Jun 28 13:31:48 1997


At Fri, 27 Jun 1997, tcab1@idt.net wrote: >
>I have a patient with relatively severe endometriosis who after 6 months on
>Depot Lupron 3.75 is still occasionally bleeding, at which time she of
>course is in considerable pain. She also denies any menopausal type
>symptoms. I have not encountered this problem with Lupron before. This
>woman is not at all overweight and gets the injections at my office, and to
>this point has not received any add back therapy. My inclination is to go
>to Depot Lupron 7.5, but would be interested in your comments and
>suggestions.
>
>Tim Brown
>Private Practice
>Long Island, New York
>
>"Life is not breath, but action . . . " Jean Jacques Rousseau

With no hot flushes, it sounds like she's not suppressed. I'm assuming this bleeding is not cyclic. I would probably check an estradiol level and maybe an endometrial stripe measurement on her, and if they're not what you think they should be, give her the 7.5 mg.

--
Laurie Lovely, MD
RE fellow, UNC-Chapel Hill




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