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BR CA 1 testingFrom: Garry E. Siegel, M.D. (garrys@mindspring.com)Fri Jun 27 22:26:57 1997
Opinions please: 40 YO ashkenazi (Eastern European descent) Jewish woman who had a 11 mm infiltrating ductal breast cancer, node negative, treated with lumpectomy/radiation/prophylactic chemo, who is about 5 years out, meaning the diagnosis was at age 35. Her mother had essentially the same diagnosis in the same breast (left, upper outer) treated the same way at age 55 or so, and is without disease, as is her daughter. Her maternal aunt recently (age 52) had an early lesion, same breast, etc., and had lump/radiation but no chemo. I think that Breast Cancer genetic testing is warranted for the patient, and if positive, I would test the other two. My rationale is if she is positive, that she should consider prophylactic oophorectomy. Furthermore, the aunt has a 28 year old daughter with no disease. There are no other adult females, but the patient has a 10 year old daughter. I have recommended testing through a nearby university center (Emory U); it will cost her about 1300 to 2000 dollars. What do ya'll think? Garry
-- Garry E. Siegel, M.D., FACOG Private Practice Roswell, Ga.
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