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Re: Low dose HRTFrom: Philip Suarez, M.D. (philip@ICSI.Net)Thu Jun 19 07:43:27 1997
> Richard Chudacoff, MD wrote: > > > Blew me out of my seat (translated: I woke out of my post-prandial slumber) > > when I heard this. I spoke to the speaker and the drug company's research > > director after the meeting, and the paper had been submitted and awaiting > > peer review. Nonetheless, pretty exciting stuff....or am I way behind the > > treatment curve again? > > I was taught in residency that 0.3mg was an perfectly adequate dose > for prevention of osteoporosis and cardiovascular changes I would tend to disagree. I think there is some evidence that even the 0.625 mg dosing may be inadequate for cardiovascular protection. I'm racking my brain trying to figure out which conference I recently attending that delivered the message that 1.25 mg is probably the more effective dose. Further, I completely agree that this low dosing would not even touch vasomotor symptoms or vaginal complications. Additionally, I have begun actually using low-dose OC's (LE 1/20, Alesse) in my patients who have undergone a surgical menopause in their 30's or 40's (who otherwise have no contraindications to OC use, of course...). They have responded FAR BETTER than when I used the "traditional" ERT dosing for menopause. Regards, Philip ----------------------------------------------------- Philip Suarez, M.D. philip@icsi.net ----------------------------------------------------- Fellow - American College Ob/Gyn
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