Lovanox vs. Heparin

From: Bill Kuyper (bkuyper@radiks.net)
Tue Sep 24 20:04:24 1996


Any ideas/comments on the following:

27 y/o morbidly obese g1 at 14 weeks gestation. Discharged from hospital yesterday by internist and oncologist where she had been treated over the past 4 days for a "very bad" superficial thrombophlebitis. W/U excluded DVT but comments made that basically every superficial vein thrombosed. Patient at baseline has bad lower extremitiy varicosities. Pregnancy was not discovered until HD #3 (we won't comment on this fact as patient had multiple x-rays/CT's during this time). Pt was sent home on Luvonox 150 mgm BID, with the plan by the hematologist that she stay on this dose for the duration of the pregnancy.

My questions are:

1. Is there enough experience with Luvanox in pregnancy to advocate it's use over Heparin?

2. If this patient should be switched to Heparin is 7500 units BID adequate? Further, does a patient such as this really need to be fully anticoagulated during the pregnancy?





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