Re: ACOG Rh antibody testing--whoa

From: Gordon M. Goldman (goldmang@medicine.wustl.edu)
Sun Sep 22 13:38:51 1996


On Fri, 20 Sep 1996 MNudel@aol.com wrote:

> I believe that these recommendations are being misinterpreted by listers. My
> interpretation is that these recommendations are for following the patient
> (who is antibody positive) with titers. This can be done until the titers
> reach >1:8. I include the text of the ACOG bulletin for your own

> hyperbilirubinemia treated by phototherapy, antibody titers are the
> initial step of management. An antibody titer should be determined at
> the first prenatal visit, at 20 weeks of gestation, and approximately
> every 4 weeks thereafter. When the antibody titer is 1:8, whether
> directed to D or another paternal antigen capable of causing severe
> erythroblastosis, no intervention is necessary; when the titer is 1:16
> in albumin or 1:32 by indirect antiglobulin (indirect Coombs test),
> amniocentesis or percutaneous umbilical cord blood sampling
> (cordocentesis) should be considered (5).
>

This seems open to various interpretations. Perhaps we should get some clarification from the college?

Gordon





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