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Re: a triple translocationFrom: Allen Gardner (allen.gardner@utoronto.ca)Mon Sep 9 14:41:26 1996
On Mon, 9 Sep 1996 10:41:05 -0400 T-H Bui, Clinical Genetics, Karolinska Hospital wrote:
> From: T-H Bui, Clinical Genetics, Karolinska Hospital
rearrangements( CCR) which has
> been defined as structural rearrangements involving at
least three
> chromosomes and three or more chromosome breakpoints. CCR
appears to be
> balanced in your patient as I can understand (was it de novo or familial?). ======================================= The patient was adapted, so I don't know about her family. I suppose one could argue both ways on this. The more complex the translocation the less likely it is de novo because of all the steps involved, or the more complex it is the less likely it is inherited because meiosis is more difficult to be successful. Do you know of any studies that addressed this? Allen. H. Allen Gardner MD Genetics Oshawa General Hospital 24 Alma Street Oshawa, Ontario L1G 2B9
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