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Re: Norplant Failures From: Richard Chudacoff, MD (richardc@bcm.tmc.edu) Fri Aug 30 09:55:59 1996 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Richard Chudacoff, MD: "Re: Politics and Medicine" Previous message: Richard Chudacoff, MD: "Re: Undocumented uterine scar" Maybe in reply to: PDBurstein@aol.com: "Norplant Failures" Don't think twins are the question, since it was probably a random, or inherited event (family history of DI/DI?) I do remember that the women who are most likely to fail on norplant are the women who have regular cyclic menses, which your brief desription suggested. Double bummer of a failure, though. >I have a 37 year old patient who has had Norplant for 3 and a half years. >She noted breast tenderness, then missed her expected period. A uhCG was >positive, and the exam consistent with dates. Transvaginal sonogram >showed twin gestations, clearly in separate sacs. The published failure >rate for Norplant is 2 per thousand per year, and when adjusted for >weight (this patient is 125 lbs) perhaps slightly lower. Altough that use >of Norplant has dropped significantly in our practice, I cannot remember >a failure in the past five years. The presence of twins seems to be >incredibly rare. I just performed a Medline search and cannot find any >mention of twins. > >I have contacted the FDA, mostly at the patient's request, as she is >concerned about the possibility of a bad batch of Norplant-fortunately we >have always recorded the lot numbers. I am waiting for follow up from the >FDA. > >Has anyone seen twins as a result result of Norplant failure? > >Paul D. Burstein, M.D. FACOG >Clinical Associate Professor >Department of Obstetrics & Gynecology >University of Wisconsin >Milwaukee Clinical Campus > -- Richard Chudacoff, MD Asst. Clinical Professor, OB/GYN Baylor College of Medicine Baylor MedCare 1601 Main, STE 505 Richmond, TX tel 713-344-0277 fax 713-344-0288 The knowledge of the world is only to be acquired in the world, and not in a closet. Lord Chesterfield Next message: Richard Chudacoff, MD: "Re: Politics and Medicine" Previous message: Richard Chudacoff, MD: "Re: Undocumented uterine scar" Maybe in reply to: PDBurstein@aol.com: "Norplant Failures"

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