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Micronized EstradiolFrom: John Hellriegel (jhellrie@ubmedd.buffalo.edu)Fri Aug 30 00:11:42 1996
R. Daniel Braun said: “Micronized estradiol manufactured in the laboratory is the most pure form of The naturally occurring estrogen known to man. My wife is on it and if I were a woman, I would probably be on it.” I have a few patients who claimed that estradiol did not relieve their symptoms for a full 24 hours -- qd dosing. When I changed them to bid dosing the symptoms were relieved. (For example, 2 mg in the AM was changed to 1 mg in the AM and PM.) I credit this phenomenon to the more rapid metabolism of estradiol compared to the other estrogenic compounds, i.e. Premarin or the esterified estrogens. Have others had this experience?
-- John Hellriegel, MD
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