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Re: Progesterone therapy From: T Dubose (tjdubose@chrp.uams.edu) Mon Aug 19 12:36:39 1996 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Ralf Witteler: "Re: VAG. HYSTERECTOMIA" Previous message: Arthurfree@aol.com: "Re: Malpractice Insurance:need advice" Maybe in reply to: pauleun@MEM.po.com: "Progesterone therapy" Next in thread: Richard Chudacoff, MD: "Re: Progesterone therapy" I have always had the impression that estrogen had a vasodilative effect on the vessels of reproduction and that catacolomines had a vasoconstricting effect, also that progesterone alone had a constricting effect (Resnik R; The endocrine regulation of uterine blood flow in the nonpregnant uterus: A Review; Am J. Obstet. Gynecol, 1981; 140:151-156). What is the effect of progesterone on uterine perfusion? Or is there a percent estrogen/progesterone which moderates perfusion? Can it be that it is the lack of perfusion which causes some recurrent spontaneous abortions? I think so, especially were stress and catacolomines are a concern. We developed an argument for this in our publication, but it was really searching literature to confirm what we were seeing. See: DuBose, Hill, Cunyus, et al; Sonography of Menstrual Changes in Arcuate Uterine Blood Vessel Diameters; J Cardiovascular Ultrasonography, 1985; 4:243-251. This info is dated now, the research was done before the advent of endovaginal transducers. However, it seems our observations of changes in uterine vessel diameters throughout menstrual cycles might be related. Peace, Terry J. DuBose, M.S., RDMS; Assistant Professor Program Director, Diagnostic Medical Sonography University of Arkansas for Medical Sciences, tjdubose@chrp.uams.edu http://www.io.com/~dubose/ VOICE: 501-686-6510 FAX: 501-686-5613 Now is the time for all good folks to come to the aid of the Earth. -- ---------- From: DoctorJoe@aol.com To: Multiple recipients of list Subject: Re: Progesterone therapy Date: Monday, August 19, 1996 10:09AM <<No one seems to be able to provide me with any data to support this practice but this gives both the physician and the patient that something is being done to prevent miscarriage. In my opinion, the only patients who may benefit from this would be those with recurrent spontaneous abortions and have documented luteal phase defect. I don't think we know the science behind it, probably because the causes of "bleeding in the first trimester" are multiple. Next message: Ralf Witteler: "Re: VAG. HYSTERECTOMIA" Previous message: Arthurfree@aol.com: "Re: Malpractice Insurance:need advice" Maybe in reply to: pauleun@MEM.po.com: "Progesterone therapy" Next in thread: Richard Chudacoff, MD: "Re: Progesterone therapy"

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