Re: Dx Challenge at BTGH, questions answered and update

From: Dr. Carlos Chase (drchase@caribnet.net)
Mon Oct 30 14:50:00 1995


>Dr. Chase...
> Will standard blood culture reveal Leptospirosis? I will order leptospira
> titers.
>Updated results...
> Preliminary reading of thick smear for malaria negative. No cultures
> growing anything yet. Patient spiked twice yesterday to 103 and 104..
> She responded to a cooling blanket. I am hesitant to use acetominophen
> in this patient with her picture of liver insult. Any support for this..
> Is there a better antipyretic choice? Other serologies not ready....

Leptospirosis- Blood cultures , urine cultures may reveal organism with dark field microscopy. Note that direct culture is notoriously difficult. Leptospira titres may be more helpful.

I also saw dengue fever as a suggestion - tires acute and convalescent can identify individuals exposed, remember though that there are 4 serotypes.

I would suggest the old fashioned:- fan therapy, alcohol sponge until liver enzymes are normal. May I ask what her urine output has been like?

Dr. Carlos Chase MBBS, DGO Department of Obstetrics and Gynaecology Queen Elizabeth Hospital Bridgetown Barbados

E-mail: drchase@caribnet.net





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