Re: role of methyle dopa in preeclampsia

From: Robert J. Carpenter, Jr. MD, JD (zygote@icsi.net)
Sat Feb 28 14:50:24 2009


Aldomet has NO role.

Best agents are nifedipine 10mgs q20minutes x 5 dose max or ascending labetalol dosing 20,40,40,80,80mgs iv q20 min, with cross over to opposite agent if primary one fails. It takes average 1.8 doses with Nifedipine and 2.8 doses with labetalol to control pressures.

Nifedipine is a ddihydropyridine and is not contraindicated with MgSO4. It is not a myocardial depressant. VERAPAMIL is absolutely contraindicated since it is a myocardial depressant.

For primary articles see multiple ones by Steve Vermillion. 1999-2001 - really good randomised controlled studies

On 28 Feb 2009 at 10:54, DoctorJoe@aol.com wrote:

>
> In a message dated 2/28/09 4:22:03 AM, drpreetisverma@yahoo.com writes:
>
> what is the role of methyle dopa in primi at 36 weeks with severe pre eclamcia
>
> The proper treatment of severe preeclampsia at that gestational age is delivery.
>
> Methyldopa can be used for blood pressure control, but it works so slowly, it probably won't be
> very helpful. A faster-acting drug such as hydralazine or one of the beta-blockers would be more
> effective in the short period of time you have while preparing for delivery.
>
> Joe P.
>

> w.freecreditreport.com%2Fpm%2Fdefault.aspx%3Fsc%3D668072%26hmpgID%3D62%26bcd%3
> DfebemailfooterNO62)

--
Robert J. Carpenter, Jr. MD, JD
6624 Fannin, #2720
Houston, TX 77030
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"Life is difficult" The Road Less Travelled by Scott Peck





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