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Re: Short cervix progesterone and twins From: Henry Gregor (henrygregor@yahoo.com) Tue Sep 30 09:52:56 2008 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: JD Stewart,MD: "Re: Ob: IVF candidate" Previous message: Gordon Goldman: "Re: Ob:  IVF candidate" In reply to: R. Daniel Braun: "Re: Short cervix progesterone and twins" Next in thread: R. Daniel Braun: "Re: Short cervix progesterone and twins" Reply: R. Daniel Braun: "Re: Short cervix progesterone and twins" Re efficacy in twin gestations...is anyone aware of work that looked at twin pregnancies in different categories of twins in a patient with a prior hx PTL in a singleton pregnancy, vs twins in a patient without prior hx of PTL?  I have a bit of an emotional interest here, I suppose, as I had a patient in the first category who elected on an informed consent basis to go with progesterone in her twin gestation, given her past hx singleton PTL, ... only to get flamed by a local MFM who told her the mgt we agreed on was without merit. (Pt did go to 36 weeks, though of course its only an anedcotal case observation.) Hank --- On Tue, 9/30/08, R. Daniel Braun <rd.braun@gmail.com> wrote: From: R. Daniel Braun <rd.braun@gmail.com> Subject: Re: Short cervix progesterone and twins To: "Multiple recipients of list OB-GYN-L" <ob-gyn-l@mail.obgyn.net> Date: Tuesday, September 30, 2008, 8:11 AM The first study by Johnson in the 70's, included twins and trips. It did indeed show efficacy. Dan On Mon, Sep 29, 2008 at 10:43 PM, Garry E. Siegel, M.D. <garrys@mindspring.com> wrote: Nope. Needs steroids (done, I'm sure). My recollection is that 17 alpha hydroxyprogesterone caproate is advised for prematurity prevention in singletons beginning at 16 weeks with no known benefit for twins. Garry At Mon, 29 Sep 2008, Andrew Folley wrote: > >Morning rounds yesterday.  Residents have 28 weeks Di/Di twins with short cervix  12 mm.  They have her on progesterone suppository 200mg q hs. >I say fine but no evidence to support benefit of progesterone suppos in twins.  Benefit for delaying preterm birht only in singletons (de Fonseca NEJM august 2007)  MFM disagress with me.  Anyone know of any new articles study that show benefit for progesterone and twins? andy > >. -- Garry E. Siegel, M.D. Private Practice Roswell, GA -- R. Daniel Braun, MD  FACOG(L)  ABMP  CMTh Professor Emeritus Dept. of Obstetrics and Gynecology Indiana U. School of Medicine R. Daniel Braun       "Science without Religion is LAME; Religion without Science is BLIND"                        Einstein 1941 Next message: JD Stewart,MD: "Re: Ob: IVF candidate" Previous message: Gordon Goldman: "Re: Ob:  IVF candidate" In reply to: R. Daniel Braun: "Re: Short cervix progesterone and twins" Next in thread: R. Daniel Braun: "Re: Short cervix progesterone and twins" Reply: R. Daniel Braun: "Re: Short cervix progesterone and twins"

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