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Re: 12 hour PROM and GBS From: Dean Huffman . (dean@thehuffpeople.net) Mon Sep 29 20:47:04 2008 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Gordon Goldman: "Surprise, Surprise" Previous message: Raymond Stephen: "Re: 12 hour PROM and GBS" .. Kofi Amankwah was my mentor and he always said that multiple gestations require more steroids (e.g., beta methasone). He never was able to give me a reference, however. Dean Huffman - - - - From: Raymond Stephen <Stephen.Raymond@dhhs.tas.gov.au> Subject: Re: Short cervix progesterone and twins Date: Sep 29, 2008 6:08 PM There seems to be some merit in the theory that twin pregnancies require double the dose of steroid given to singletons to have the same effect. Can't lay my hands on the reference right now but someone did a study on clearance of steroids in twins and found that it disappeared more quickly. Steve Raymond Ph (03)62227898 Cell 0438372395 -----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Dr. John Provatopoulos B.Sc. M.D.C.M. F.R.S.C. Sent: Monday, 29 September 2008 8:45 PM To: Multiple recipients of list OB-GYN-L Subject: Re: Short cervix progesterone and twins At Mon, 29 Sep 2008, Andrew Folley wrote: > >Morning rounds yesterday. Residents have 28 weeks Di/Di twins with short cervix 12 mm. They have her on progesterone suppository 200mg q hs. >I say fine but no evidence to support benefit of progesterone suppos in twins. Benefit for delaying preterm birht only in singletons (de Fonseca NEJM august 2007) MFM disagress with me. Anyone know of any new articles study that show benefit for progesterone and twins? andy > >. As far as I know no evidence for use of progesterone in twins, most important thing here is to make sure MOM gets celestone, the the proof for celestone in twins is also not as rigourous as for singleton. -- Take care, John Next message: Gordon Goldman: "Surprise, Surprise" Previous message: Raymond Stephen: "Re: 12 hour PROM and GBS"

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