Re: ASCUS/ Positive HPV in elderly

From: Joanne Bulley, MD (islesannie@gmail.com)
Thu Mar 27 19:12:38 2008


I would colpo. This is what it is all about. the estimates from the research over the last 30 years suggests that by age 50, 80% of adults have been infected and 90% or so clear the virus. The others carry it for life and those are the folks who are at risk for cervical cancer late in life.

With some of my 80-something patients that I have managed (Some with oncology consult) - the change to ASCUS and / or LSIL was concurrent with their other medical issues heading downhill - and their other end organ issues usually took them before the cervical changes (one was end stage pulmonary disease and the other was cardiac).

With my GynOnc's involvement - we keep the vagina estrogenized (cream or Vagifem or Estring) and monitor to see that the cervical epithelium stays at LSIl or CIN 1 or less. Interestingly, whenever they stop the estrogen, their pap is worse.

In my 70 & 80 yo women with CIN and HRHPV - some appear to all questions to have been in a lifelong mutually monogamous relationship. Others were widowed or divorced - celibate for years and then met with and had a new partner (with or without marriage) and likely got their HRHPV from the new partner.

Joanne

At Thu, 27 Mar 2008, Kathleen Griffin, M.D. wrote: >
>I have an 80 year old patient who had hematuria and her PMD did a Pap
>smear, which came back ASCUS, endocervical cells absent, positive for
>high risk HPV by Digene Hybrid Capture II testing. A repeat test was
>also positive.
>Her entire lifetime her Pap smears were always normal, and her last
>sexual activity was 10 years ago.
>She is taking "natural" compounded HRT.
>Could this be false positive? Is it indicated to do colposcopy?
>
>--
>Kathleen Griffin, M.D.
>

--
Joanne Bulley, MD
solo gyn
Keene, NH

"enjoying" the results of epidural depomedrol for a bulging L4-5 disc. Ruins the end of the ski season and start of hiking. Bah Humbug





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