OB-GYN-L Messages for January, 2008: Re: Interesting Sisters

Re: Interesting Sisters
From: FRANCES WREN (fwren@shaw.ca)
Tue Jan 22 14:53:11 2008

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In reply to: Dean Huffman .: "Interesting Sisters"
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there certainly seems to be a genetic thing related to PIH esp early cases.... but exactly what and why I don't think is elucidated as yet ..and there are probably variants...early versus late PIH...etc frances wren

>----- Original Message -----
From: "Dean Huffman ." <dean@thehuffpeople.net> Date: Tuesday, January 22, 2008 1:19 pm Subject: Interesting Sisters To: Multiple recipients of list OB-GYN-L <ob-gyn-l@mail.obgyn.net>
> .
>
> This is an interesting e-mail I recently received about two
> patients I had seen
> (I have blocked out their names).
>
> What do you think.
>
> - - - -
>
> FYI
>
> I meant to tell you about this earlier. You saw two patients of
> mine and I
> wanted to complete the story.
>
> 1)****** -- Seen at 16 weeks and noted to have reverse diastolic
> flow. Presented
> at about 21-22 weeks with severe PIH and ended up with an IUFD
> within 6-12
> hours. Subsequent work-up showed only a mild Protein S deficiency.
>
> 2)****** -- Seen at 18-20 weeks and noted to have absent
> diastolic flow.
> Presented at 23 weeks with severe PIH and transferred to ******
> where she had
> intrapartum demise. Ended up with full-blown HELLP. Work-up
> negative although I
> didn't see Protein S testing.
>
> After the fact, I found out they are SISTERS. What do you think?
>

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<DIV>there certainly seems to be a genetic thing related to PIH esp early cases....</DIV> <DIV>but exactly what and why I don't think is elucidated as yet ..and there are probably variants...early versus late PIH...etc</DIV>
><DIV>frances wren ----- Original Message ----- From: "Dean Huffman ." <dean@thehuffpeople.net> Date: Tuesday, January 22, 2008 1:19 pm Subject: Interesting Sisters To: Multiple recipients of list OB-GYN-L <ob-gyn-l@mail.obgyn.net> > . > > This is an interesting e-mail I recently received about two > patients I had seen > (I have blocked out their names). > > What do you think. > > - - - - > > FYI > > I meant to tell you about this earlier. You saw two patients of > mine and I > wanted to complete the story. > > 1)****** -- Seen at 16 weeks and noted to have reverse diastolic > flow. Presented > at about 21-22 weeks with severe PIH and ended up with an IUFD > within 6-12 > hours. Subsequent work-up showed only a mild Protein S deficiency. > > 2)****** -- Seen at 18-20 weeks and noted to have absent > diastolic flow. > Presented at 23 weeks with severe PIH and transferred to ****** > where she had > intrapartum demise. Ended up with full-blown HELLP. Work-up &gt
9; negative although I > didn't see Protein S testing. > > After the fact, I found out they are SISTERS. What do you think? > > > > > </DIV>
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Next message: GIN11153@aol.com: "Re: Quintuplets"
Previous message: Garry E. Siegel, M.D.: "Re: Gen: What would you do"
In reply to: Dean Huffman .: "Interesting Sisters"
Next in thread: Dr. John Provatopoulos B.Sc. M.D.C.M. F.R.S.C.: "Re: Gen: What would you do"
Reply: Dr. John Provatopoulos B.Sc. M.D.C.M. F.R.S.C.: "Re: Gen: What would you do"

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