Re: Tubal Pregnancy--management

From: Terrence.Jones@kp.org
Tue Jan 22 13:50:56 2008


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Sorry for the late entry, just catching up. Was the situation You have recently seen (multiple with titres above singleton discriminatory zone) associated with a 48 hour f/u titre of < 50% rise, and another 72 hour f/u titre also of < 50% rise? /tj

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evsono@pipeline.com (art fougner, md) Sent by: ob-gyn-l@obgyn.net 01/19/2008 10:22 Please respond to ob-gyn-l@obgyn.net

To Multiple recipients of list OB-GYN-L <ob-gyn-l@mail.obgyn.net> cc

Subject Re: Tubal Pregnancy--management

A word of caution for those who would give MTX in a stable patient simply because their HCG comfort zone has been exceeded - Multiple Pregnancy. Levels of HCG may be significantly elevated prior to first visualization on sonar. Having recently seen this situation, I urge all to keep this in mind, prior to interrupting an early twin intrauterine pregnancy.

Of course, that's just my opinion. I could be wrong.

Art

At Sat, 19 Jan 2008, Dr. John Provatopoulos B.Sc. M.D.C.M. F.R.S.C. wrote: >
>At Sat, 19 Jan 2008, Garry E. Siegel, M.D. wrote:
>>
>>20 YO P0, seen in ER and office as follows:
>>
>>1/13--acute abdominal pain requiring narcotics, got better. Exam per ER
>>MD negative, HCG 1300, Hemoglobin 15, ultrasound empty uterus and 3 cm.
>>cyst left side.
>>
>>1/15--asymptomatic except spotting, HCG 1900, Hemoglobin 15, negative
>>exam by me. Ultrasound no change.
>>
>>1/18--HCG now 2800 from 1/17, progesterone 5.4 from 1/17, exam and
>>ultrasound unchanged.
>>
>>Would you have made a dispostion on 1//15?
>>
>>If so, what?
>>
>>If not, now it is 1/18 and I made a dispostion.
>>
>>Would you:
>>
>>1. D and C, frozen section, and scope if negative?
>>2. D and C, await pathology, give methotrexate?
>>3. Give methotrexate primarily?
>>
>>More to discuss once replies come in. . .
>>
>>Garry
>
>First I get the feeling this is a very wanted pregnancy, in which case I
>would also have done nothing on the 15th.; 1300 -1900 is not good but I
>have seen normal pregnancies with similar changes.
>
>I would have gone with D&C and scope, I don't find frozen section very
>helpfull. Having had to take care of about half a dozen MTX disasters
>in the the last decade, I don't feel comfortable using it in my practise
>setting.
>
>I recently had a similar case, BHCG 1000-1500 -1700, Q 2daily then 1700
>again, told patient not looking good. brought in for D&C and scope; D&C
>looked like mostly deciduia so scoped and saw normal tubes but had a
>small fibroid 3cm fibroid on back wall of uterus, I thought it was a
>septum on D&C, in view of normal tubes repeated D&C concentrating
>suction behind the fiboid and got more tissue. Yes the pregnancy was
>stuck behind and to the side of the fibroid.
>
>--
> Take care, John
>

--
art fougner, md
"May The Wings of Liberty Never Lose a Feather." - Jack Burton

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<br><font size=2 face="sans-serif">Sorry for the late entry, just catching up. Was the situation You have recently seen (multiple with titres above singleton discriminatory zone) associated with a 48 hour f/u titre of < 50% rise, and another 72 hour f/u titre also of < 50% rise? /tj<br> <br> </font><font size=1 color=blue face="Arial"><b>NOTICE TO RECIPIENT:</b></font><font size=1 face="Arial"> &nbsp;If you are not the intended recipient of this e-mail, you are prohibited from sharing, copying, or otherwise using or disclosing its contents. &nbsp;If you have received this e-mail in error, please notify the sender immediately by reply e-mail and permanently delete this e-mail and any attachments without reading, forwarding or saving them. &nbsp;Thank you.<br> </font> <br> <table width0%> <tr valign=top> <td width@%><font size=1 face="sans-serif"><b>evsono@pipeline.com (art fougner, md)</b> </font> <br><font size=1 face="sans-serif">Sent by: ob-gyn-l@obgyn.net</font> <p><font size=1 face="sans-serif">01/19/2008 10:22</font> <table border> <tr valign=top> <td bgcolor=white> <div alignÎnter><font size=1 face="sans-serif">Please respond to<br> ob-gyn-l@obgyn.net</font></div></table> <br> <td widthY%> <table width0%> <tr> <td> <div align=right><font size=1 face="sans-serif">To</font></div> <td valign=top><font size=1 face="sans-serif">Multiple recipients of list OB-GYN-L <ob-gyn-l@mail.obgyn.net></font> <tr> <td> <div align=right><font size=1 face="sans-serif">cc</font></div> <td valign=top> <tr> <td> <div align=right><font size=1 face="sans-serif">Subject</font></div> <td valign=top><font size=1 face="sans-serif">Re: Tubal Pregnancy--management</font></table> <br> <table> <tr valign=top> <td> <td></table> <br></table> <br> <br><font size=2><tt>A word of caution for those who would give MTX in a stable patient<br> simply because their HCG comfort zone has been exceeded - Multiple<br> Pregnancy. &nbsp;Levels of HCG may be significantly elevated prior to first<br> visualization on sonar. &nbsp;Having recently seen this situation, I urge all<br> to keep this in mind, prior to interrupting an early twin intrauterine<br> pregnancy.<br> <br> Of course, that's just my opinion. I could be wrong.<br> <br> Art<br> <br> At Sat, 19 Jan 2008, Dr. &nbsp;John Provatopoulos B.Sc. &nbsp;M.D.C.M. &nbsp;F.R.S.C.<br> wrote:<br> ><br> >At Sat, 19 Jan 2008, Garry E. Siegel, M.D. wrote:<br> >><br> >>20 YO P0, seen in ER and office as follows:<br> >><br> >>1/13--acute abdominal pain requiring narcotics, got better. &nbsp;Exam per ER<br> >>MD negative, HCG 1300, Hemoglobin 15, ultrasound empty uterus and 3 cm.<br> >>cyst left side.<br> >><br> >>1/15--asymptomatic except spotting, HCG 1900, Hemoglobin 15, negative<br> >>exam by me. &nbsp;Ultrasound no change.<br> >><br> >>1/18--HCG now 2800 from 1/17, progesterone 5.4 from 1/17, exam and<br> >>ultrasound unchanged.<br> >><br> >>Would you have made a dispostion on 1//15?<br> >><br> >>If so, what?<br> >><br> >>If not, now it is 1/18 and I made a dispostion.<br> >><br> >>Would you:<br> >><br> >>1. &nbsp;D and C, frozen section, and scope if negative?<br> >>2. &nbsp;D and C, await pathology, give methotrexate?<br> >>3. &nbsp;Give methotrexate primarily?<br> >><br> >>More to discuss once replies come in. . .<br> >><br> >>Garry<br> ><br> >First I get the feeling this is a very wanted pregnancy, in which case I<br> >would also have done nothing on the 15th.; 1300 -1900 is not good but I<br> >have seen normal pregnancies with similar changes.<br> ><br> >I would have gone with D&C and scope, I don't find frozen section very<br> >helpfull. &nbsp;Having had to take care of about half a dozen MTX disasters<br> >in the the last decade, I don't feel comfortable using it in my practise<br> >setting.<br> ><br> >I recently had a similar case, BHCG 1000-1500 -1700, Q 2daily then 1700<br> >again, told patient not looking good. &nbsp;brought in for D&C and scope; D&C<br> >looked like mostly deciduia so scoped and saw normal tubes but had a<br> >small fibroid 3cm fibroid on back wall of uterus, I thought it was a<br> >septum on D&C, in view of normal tubes repeated D&C concentrating<br> >suction behind the fiboid and got more tissue. &nbsp;Yes the pregnancy was<br> >stuck behind and to the side of the fibroid.<br> ><br> >--<br> > &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Take care, John<br> ><br> <br> --<br> art fougner, md<br> &quot;May The Wings of Liberty Never Lose a Feather.&quot; - Jack Burton<br> </tt></font> <br>





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