Re: Gyn: Endometrial Cells on pap

From: Harrison Sheld (hsheld@vwestm.net)
Sun Dec 9 16:50:54 2007


I understand and appreciate the point about relative risks, I did not mean the findings should be not necessarily be investigated. What I meant was: if a matched population of 1784 asymptomatic women without endometrial cells on their paps also have a 2% incidence of "pathology", then what was found in the report could be found in the asymptomatic population. Using the analogy with trisomy 21, then all postmenopausal women should have endometrial sampling because 2% of them may have "pathology". Perhaps it is a with good reason that the recommendation about the frequency of paps in asymptomatic postmenopausal women suggests longer intervals to age 70 and then in the face of a normal pap history, no more paps.

Harrison

art fougner, md wrote: > We think about amniocentesis for Down's risks much less than 2%. Is
> endometrial sampling for most women more invasive than amnio? Or is an
> infant with Down's more intolerable an outcome than cancer? Just asking
> ..
>
> Art
>
> At Sun, 09 Dec 2007, Harrison Sheld wrote:
>
>> The question that should be asked as a followup to this study (
>> Am J Obstet Gynecol. 2007 Jun;196(6):568.e1-5; discussion 568.e5-6.
>> Endometrial cells identified in cervical cytology in women > or = 40
>> years of age: criteria for appropriate endometrial evaluation.) is: in
>> 1784 asymptomatic women over 50 who have no endometrial cells on a
>> cytology examination, matched with the 1784 with endometrial cells on
>> pap, would pathology be found? Of the 1784 patients, only 440 (25%) had
>> "pathology," of which 4 had complex endometrial hyperlasia with atypia,
>> and 4 had adenocarcinoma, for a total of less than 2% (8/440). Pathology
>> in the other 432 is not cited. The abstract did not include information
>> on symptomatology of all patients with pathology. I don't find value in
>> this study as reported.
>>
>> --
>> Harrison Sheld, M.D.
>> Las Vegas, Nevada
>>
>
> --
> art fougner, md
> "May The Wings of Liberty Never Lose a Feather." - Jack Burton
>





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