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Re: Methadone Pregnancy Info From: sharon@methadonesupport.org Sun Dec 2 14:15:35 2007 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: sharon@methadonesupport.org: "Re: Methadone Pregnancy Info" Previous message: ainsron: "Re: Methadone Pregnancy Info" Know the study well, not all the well done ("retrospective, it was neither blinded nor randomized. Decisions regarding duration of neonatal hospitalization, need for treatment, and neonatal abstinence score are generally considered to be objective, but clinicians were aware of maternal drug use and methadone dosage"). It was a retrospective study that looked back over 11 yrs. There was also a study in 2003 done by Berghella, et al revealed the opposite findings of Dashe's study. Also, more interesting is the fact that in a study that looked at whether cord blood concentrations of methadone predict the severity of NAS (Archives of Disease in Childhood Fetal and Neonatal Edition 2004;89:F390-F393) it was found that maternal methadone dose did not predict the need for treatment. However, infants who required treatment had significantly lower methadone concentrations in cord blood than the group who did not receive treatment.   I have a theory about that if anyone is interested!   Sharon Sharon Dembinski,MS,RNP,CMA Nurse Practitioner Certified Methadone Advocate Methadone Support Org Advisory Board Discovery House: The Center for Recovery and Hope Kent Hospital Mothers On Methadone (MOM) Program 508 864-0311 http://www.methadonesupport.org/Pregnancy.html > -------- Original Message -------- Subject: RE: Methadone Pregnancy Info From: "ainsron" <ainsron@sbcglobal.net> Date: Sun, December 02, 2007 3:02 pm To: Multiple recipients of list OB-GYN-L <ob-gyn-l@dns.obgyn.net> There is a good article that addresses it in the Green Journal, v100, #6, 12/02, Jodi Dashe, et.al, “Relationship between maternal methadone dosage and neonatal withdrawal.  It can occur on as low as 20mg/d (12% of mothers) and increases to 90% on mothers receiving 40mg/d or more.  It’s almost a linear correlation and also correlates to duration of neonatal hospitalization.   Ronald E. Ainsworth, MD, FACOG   -----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of DoctorJoe@aol.com Sent: Thursday, November 29, 2007 8:29 PM To: Multiple recipients of list OB-GYN-L Subject: Re: Methadone Pregnancy Info   Sharon, Since you're "into" Methadone and pregnancy, what's the rough upper limit of maternal dose of Methadone that you can use WITHOUT getting withdrawal symptoms in the neonate? Joe P. ************************************** Check out AOL's list of 2007's hottest products. (http://money.aol.com/special/hot-products-2007?NCID=aoltop00030000000001) Next message: sharon@methadonesupport.org: "Re: Methadone Pregnancy Info" Previous message: ainsron: "Re: Methadone Pregnancy Info"

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