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Re: vaginal dysplasiaFrom: ainsron (ainsron@sbcglobal.net)Tue Nov 27 10:36:03 2007
I don't have the article, but it should summarize the recommendations for treatment. On the other hand, if it's only LGSIL, why treat at all? Most studies show a fairly high clearance and low progression over time. Repeat pap and colpo in six months would be reasonable. Am J Obstet Gynecol 1995 Apr;172(4 Pt 2):1354-9 Human papillomavirus infection and therapy with interferon. Department of Obstetrics and Gynecology, University of Louisville School of Medicine, KY 40202, USA. The studies summarized have shown that therapy of condylomata acuminata with interferon is effective. The route of administration does not appear to influence the results; the intralesional, intramuscular, and subcutaneous routes were effective. Additional research is required to determine whether the natural interferon or recombinant product is superior. The appropriate administration schedule may also not have been attained. Ronald E. Ainsworth, MD, FACOG -----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Richard Chudacoff Sent: Tuesday, November 27, 2007 9:06 AM To: Multiple recipients of list OB-GYN-L Subject: vaginal dysplasia I have a patient with a low-grade squamous intraepithelial lesion, and high risk HPV. Colposcopy only noted a semicircular rang of koilocytic changes in the posterior fornix. I'm sure there is a medical management protocol using interferon, but I cannot find a reference. It seems silly to try to remove this surgically. Can anyone help me? Richard Chudacoff, MD, FACOG Las Vegas International Center for Advanced Gynecologic Care (Specializing in minimally and non-invasive surgery) 2481 Professional Court Las Vegas, NV 89128 TEL: 702-485-8893 FAX: 702-974-0945 www.lasvegasgyncenter.com <http://www.lasvegasgyncenter.com/> www.exablateoflasvegas.com <http://www.exablateoflasvegas.com/> The information in this e-mail may be confidential and/or privileged. If you are not the intended recipient or an authorized representative of the intended recipient, you are hereby notified that any review, dissemination or copying of this e-mail and its attachments, if any, or the information contained herein is prohibited. If you have received the e-mail in error, please immediately notify the sender by return e-mail or phone and delete this e-mail. Thank you.
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