Re: 17 oh progesterone

From: Elrod, Darryl G Maj 48 MDOS/SGOBO (Darryl.elrod@LAKENHEATH.AF.MIL)
Fri Jun 8 10:53:29 2007


I agree, the first two don't fit any protocol I've ever read for benefit from progesterone. The last one you could certainly make an argument for.

Glen

________________________________

From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of

--
________________________________
Charlie Chambers
Sent: Friday, June 08, 2007 4:12 PM
To: Multiple recipients of list OB-GYN-L
Subject: Re: 17 oh progesterone

I think that I would be reluctant to treat in the first two. The 34 week with PROM seems much more reasonable.

On Jun 8, 2007, at 7:47 AM, Andrew Folley wrote:

I have 3 ladies I am considering starting on 17 OH P at 20 weeks. #1 had an incompetent cervix in first pregnacy with rescue cerclage at 24 weeks and preterm deliviery at 29 weeks. #2 developed severe preeclampsia and and was induced and delivered early at 28 weeks. Finally #3 more delivered second baby at 34 weeks following PROM. Do you think it is inappropriate to manage them with weekly 17 OH-P at 18 weeks etc??

From: garrys@mindspring.com (Garry E. Siegel, M.D.)

Reply-To: ob-gyn-l@obgyn.net

To: Multiple recipients of list OB-GYN-L <ob-gyn-l@dns.obgyn.net>

Subject: Re: Ob: PP hemorrhage in a VBAC--why do we VBAC, anyway :)?

Date: Thu, 7 Jun 2007 22:51:27 -0500

Good question and comment, and I was raised to do so, also, and still

do. However, I explore every uterus after delivery if possible (i.e. if

hurts/no epidural, I likely don't do it--if they are comfy, I do).

I am certain that the CNM did NOT explore it.

Garry

At Thu, 7 Jun 2007, Marie Harkins wrote:

>

>When I first started to work in obstetrics (mid 80's) the

hospital

>policy for VBAC included manual exploration of the uterus after

>delivery. Some of the older docs did it then, no one does it now.

>Do any of you still do this, or did you do it at one time? Do you

>think it would have made a difference in this case?

>

>--

>Marie Harkins, CNM

>Ithaca, NY

>

>On Jun 7, 2007, at 4:24 PM, Garry E. Siegel, M.D. wrote:

>

>> The case was straightforward; I just posted it this way to generate

>> discussion.

>>

>> She is thin, and I reopened her low transverse skin incision in a

>> Maylard/semi-Maylard fashion (that's how I do sections) and didn't

>> take

>> the inferior epigastrics and had tons of room. I also did the case in

>> Allen stirrups, in case I needed vaginal access (i.e. to see if the

>> bleeding had stopped).

>>

>> Upon opening the perioteum, I expected a hemoperitoneum, yet she

>> didn't

>> have it. However, you could see clot underneath her bladder flap, and

>> the clot--easily 500 to 1000 ml.--was concealed under the bladder flap

>> and kept coming out vaginally (the vagina was full of clots, as was

>> the

>> firm uterus). The clot was from a low transverse rupture,

>> obviously of

>> the old incision, easily palpable and then visualized. The clot had

>> nicely dissected the bladder way off the incision, and I

could easily

>> access the pelvic planes necessary to safely access the

uterus and see

>> the ureters easily. The left half on the incision was mush, this was

>> her fourth (and they planned no more), so it was an easy

decision

>> to do

>> a TAH. As is often the case, the lower uterine segment and vagina

>> were

>> ballooned and distorted, but I could define the cervix and actually

>> grasp the vaginal portion of the cervix through the rupture so that I

>> could preserve the upper vagina easily.

>>

>> She got 8 units in total, and looked great this AM.

>>

>> Garry

>>

>> At Thu, 07 Jun 2007, rmodugno@aol.com wrote:

>>>

>>> Hmm... Why is he asking this?

>>>

>>> Did a laparotomy - found the uterine incision intact with a posterior

>>> blowout through the uterine vessels?

>>>

>>> Robert Modugno MD MBA FACOG

>>> Sylva, NC

>>>

>>> -----Original Message-----

>>> From: Garry E. Siegel, M.D. <garrys@mindspring.com>

>>> To: Multiple recipients of list OB-GYN-L <ob-gyn-l@dns.obgyn.net>

>>> Sent: Wed, 6 Jun 2007 7:21 pm

>>> Subject: Ob: PP hemorrhage in a VBAC--why do we VBAC,

anyway :)?

>>>

>>> 37 YO P 4004 at term

>>> #1 Term LTC/S, breech, document

>>> #2 and #3--VBACs, uneventful, our CNMs, 9 to 10 pound babies

>>>

>>> This deliver--SROM, irreg ctx., augmented. While the CNM was

>>> caring for

>>> her, I stopped in a followed her a bit. Clincal EFW 4200 g

>>>

>>> Dilatation was protracted for a multip., and she had a

couple of

>>> runs of

>>> hyperstimulation (meaning tachysystole with bradycardia) that

>>> resolved

>>> with the old Pit on/Pit off/flip sides.

>>>

>>> She progressed to complete dilation, and started with big variables.

>>> After pushing around 5 to 10 minutes, heart tones were

jumbled

>>> (FSE) and

>>> unreadable, and I watched the CNM with the head crowning, and simply

>>> whispered to her (she is a newby but a goody) to make an

>>> episiotomy, and

>>> have her push even between contractions and "get the baby out."

>>> The baby

>>> came out, all well.

>>>

>>> PP she hemorrhaged, and it was assumed by the CNMs/L and D nurses

>>> to be

>>> atonic--methergine, more pit, hemabate.

>>>

>>> When she got hypotensive, I got the call.

>>>

>>> Room exam--firm fundus 2 fingers below, no lacerations, lots of BRB.

>>> Belly soft, no complaint of shoulder pain, FWIW.

>>>

>>> Hct. 23 (was 37), quick CT showed fluid in upper abdomen, clot in

>>> pelvis, ?hematoma of uterus--we went from the CT scanner across

>>> the hall

>>> to the theater.

>>>

>>> What did I do and what did I find?

>>>

>>> Garry

>>>

>>> --

>>> Garry E. Siegel, M.D.

>>> Private Practice

>>> Roswell, GA

>>>

>>> _____________________________________________________________________

>>> ___

_____________________________________________________________________

>>> _____________________________________________________________________

>>> AOL now offers free email to everyone. Find out more about

_____________________________________________________________________ what's

>>> free

>>> _____________________________________________________________________

>>> ___

_____________________________________________________________________

>>> _____________________________________________________________________

>>> from AOL at AOL.com.

_____________________________________________________________________

>>>

>> --

>> Garry E. Siegel, M.D.

>> Private Practice

>> Roswell, GA

>

--

Garry E. Siegel, M.D.

Private Practice

Roswell, GA

_________________________________________________________________

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************************************************************************ ****

Charlie Chambers

Hood River, OR

cchamber@alumni.rice.edu

"Almost anything you do will seem insignificant but it is very important

that you do it....You must be the change you wish to see in the world"

-- Mahatma Ghandi.

************************************************************************ *******





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