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Re: Mg for ALL preeclampsia and PIH ????????From: Dr. John Provatopoulos B.Sc. M.D.C.M. F.R.S.C. (johnprov@sympatico.ca)Fri May 18 08:59:47 2007
At Fri, 18 May 2007, Andrew Folley wrote: > ?????????????? > >Take-Home Pearl: Since eclampsia is also associated with an increased risk >of maternal morbidity and neonatal morbidity, one should be cautious about >the selective use of magnesium sulfate prophylaxis. > The problem with the use of Mg S04 for mild preeclampsia is that when you get to centers with low birth rates ie less than 1500 you are likely to order it and have it mixed by a pharmacy or nurse that has never done it before, its not unusal for a 4 gram bolus to become a 40 gram bolus. There is actually a trial being started comparing labetolol Vs. MgSo4 for eclampsia prevention; if labetolol was almost as good as MgSo4 it would be the right choice for small volume centers and devolping world centers, precautions for oral or I.V. labetolol are a walk in the park compared to MgSo4.
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Take care, John
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