Re: Tumor question

From: Raymond Stephen (stephen.raymond@dhhs.tas.gov.au)
Tue Mar 6 17:06:09 2007


Haven't any great experience to draw on except the one patient I had long ago who had a similar presentation aged 25. These tumours are very sensitive to chemo and conservative management is not unreasonable. Biopsy of the mass is obviously first, and could easily be achieved laparoscopically.

Steve

________________________________

From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Dr.

--
________________________________
Montgomery
Sent: Wednesday, 7 March 2007 10:59 AM
To: Multiple recipients of list OB-GYN-L
Subject: Tumor question

Could use y'all's opinion on this one.

38 y.o. presents for exam - new to the area. History is that of having a "mixed malignant germ cell tumor" with "foci of embryonal carcinoma" in '89, at the age of 19. She had the involved ovary, as well as the tube removed and no signs of mets. Had three rounds of VP 16, Bleomycin and cisplatinum. Following that, she had three ectopics, ultimately resulting in the removal of the remaining tube. In 2004, had successful IVF resulting in term twins, and also has frozen embryos from that and strongly desires more babies.

At the time of presentation, she states that she is having symptoms similar to those she had in '89. Ultrasound shows a complex appearing mass on the remaining ovary measuring 3.7 x 4.7 cm - consistent with a similar neoplasm. Tumor markers of HCG, AFP and CA-125 pending.

Certainly needs to be explored to determine the nature of the mass, given the history.

Questions that come to mind:

1. Previous horizontal incision - now do a vertical?

2. If positive for tumor and it can be "shelled out", would anybody be conservative to retain the ovary - given the pregnancy considerations?

3. If positive for similar tumor and no signs of mets, salpingooopherectomy and leave the uterus for future pregnancy - "staging" won't be back until post-op?

4. Risk of recurrence with pregnancy?

Lynn

Lynn D. Montgomery, M.D.

Obstetrics & Gynecology, Maternal-Fetal Medicine

The Birth Center/Rocky Mountain Women's Health

1211 S. Reserve St.

Missoula, Montana, 59801

406-549-0978

fax 406-549-0987

e-mail: apgar10@qwest.net

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