Re: 2 cases

From: R. Berg (robert.berg@nyu.edu)
Mon Mar 20 13:26:39 2006


I've been using Effexor XR for about a year now, for vasomotor sx in pts who don't want HRT. I've had variable success, but some people seem to do well on it.

______________________________ Robert E. Berg, M.D., FACOG, FACS

--
______________________________
And this affects me, how?

>----- Original Message ----- From: "Joanne Bulley, MD" <islesannie@yahoo.com> To: "Multiple recipients of list OB-GYN-L" <ob-gyn-l@dns.obgyn.net> Sent: Sunday, March 19, 2006 1:03 PM Subject: GYN: 2 cases

> > Case 2. Vasomotor symptoms that are intolerable to the patient and > recurring on Estratest 1.25/2.5 > 50yo G3P3 woman S/P TAH-USO at age 22. Menopause approximately age 47 > by symptoms and FSH. Initally treated with estradiol with reasonable > results. Then vasomotor symptoms returned so changed to Estratest HS > (0.625 of conjugated estrogens and 1.25mg of methytestosterone) for the > testoterone to decrease SHBG allowing more availability of free > estrogen. She did better for about 4 months then symtpoms increased and > seh was put on the "full strength" Estratest 1.25/2.5. TSH also tested > 5.6 (lab normal of 0.3-5.5) with Anti-Thyroid peroxidase antibodies at > 2014 (normal <60) consistent with autoimmune thyroiditis. 50mcg of > levothyroxine started. Vasomotor symtoms persist. PCP says it can't be > the thyroid. TSH now 3.6 (my preferred treatment range is 1-2.9) > Levothyroxine increased to 75 mcg. I want to have her euthroid before > changing estrogen. > > My thought is to bypass the liver and go with transdermal estradiol. > > Looking for your thoughts on work up & treatment of persistent basomotor > symptoms not responding to hormones? Any other metabolic evaluation I > ought to do? > > -- > Joanne Bulley, MD > Keene, NH, USA > > "Love is indescribable and unconditional. > I could tell you a thousand things that it is not, but not one that it > is." > - Duke Ellington, American jazz artist (1899-1974). >





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