Re: Maternal deaths, and risk of misoprostol for missed AB

From: art fougner, md (evsono@pipeline.com)
Sat Mar 18 11:28:50 2006


Some feel the problem might actually be the mifepristone.

...Monty Patterson, however, noted that some researchers believe that it's the first drug, the RU-486 itself, that impairs the immune system and makes women more suspectible to deadly infection.

"They're trying to deflect this onto misoprostol ... instead of looking at the real issue, which is mifepristone and its ability to impair the immune response," Patterson said. "It's like playing Russian roulette. A woman has no idea when the bullet will be for her."

The FDA and the Centers for Disease Control had already been planning a May 11 workshop in Atlanta designed in part to better understand the rare bacteria, Clostridium sordellii, detected in Holly Patterson and the three other California women who died after taking RU-486.

A woman in Canada who died in 2001 after taking the abortion pill during clinical trials also suffered from the same type of infection.

http://www.mercurynews.com/mld/mercurynews/news/breaking_news/14126429.htm

Art

At Sat, 18 Mar 2006, igold@cox.net wrote: >
>Actually, if you read the link Fran sent, it infers that misoprostol is the problem. I actually heard on the NPR report that this was the case also. Ingrid
>>
>> From: "Gerald P. Rodríguez" <geraldpr@cybermesa.com>
>> Date: 2006/03/18 Sat PM 01:17:24 EST
>> To: Multiple recipients of list OB-GYN-L <ob-gyn-l@dns.obgyn.net>
>> Subject: Re: Maternal deaths, and risk of misoprostol for missed AB
>>
>> Today's Wall Street Journal reports that Planned Parenthood in Washington DC
>> said yesterday that it was changing its prescribing practices for the use of
>> MIFEPRISTONE (Mifprex) (RU-486) in light of two recent maternal deaths
>> associated with its use vaginally instead of orally. Its vaginal use is
>> off-label and this practice is now being implicated in the death of 6 total
>> patients from sepsis.
>>
>> Gerald P. Rodríguez, M.D., FACOG
>> Santa Fe
>>
>> ~~~~~~~~~~~~~
>> Quien calla otorga.
>> ~~~~~~~~~~~~~~
>> ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
>

>>>> ----- Original Message -----
>> From: <igold@COX.NET>
>> To: "Multiple recipients of list OB-GYN-L" <ob-gyn-l@dns.obgyn.net>
>> Sent: Saturday, March 18, 2006 9:58 AM
>> Subject: Maternal deaths, and risk of misoprostol for missed AB
>>
>> > In light of the recent news linking maternal deaths to use of vaginal
>> > administation of misoprostol, what do you think of continuing its use for
>> > missed AB? Do you think oral administation would reduce the risk? Why?
>> > From what I understand, 6 maternal deaths have now been attributed to
>> > vaginal use of misoprostol (my sources are NPR driving home from work last
>> > night, and this morning's Arizona Republic newspaper) Thanks, Ingrid Gold,
>> > CNM, Phoenix
>> >
>>

--
art fougner, md
Support Free Speech
Buy Danish!




use when must restrict search to only the ob-gyn-l forum...
Enter search keywords:
Returns per screen: Require all keywords:

Return to  OB-GYN-L Mail a New Message to the Forum: ob-gyn-l@obgyn.net
Forum Administrator: geffrey.klein@obgyn.net
Report Technical Problems: webmaster@obgyn.net
Last Updated: Tue Sep 2 05:07:00 2008

The American Medical Association is no longer designating CME hours for AMA Category II CME credit. However, physicians themselves may self designate learning activities as Category II CME credit hours if they feel it is of sufficient educational merit and meets the formal definitions of continuing medical education. OBGYN.net believes these interaction in this forum meets these criteria. For further information see the AMA web site.