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Re: Breast cancerFrom: Ricardo Savaris (rsavaris@hcpa.ufrgs.br)Fri Oct 28 20:19:06 2005
At Fri, 28 Oct 2005, Atkinson, Samuel M wrote: >5. MRI is a better detector of breast cancers but cost is >prohibitive except in high risk/familial ca pts. Finding out if one had >the gene is probably money better spent than routine MRI's of breast. I disagree with your opinion. There is an article from NEJM (Kriege M, Brekelmans CT, Boetes C, et al. Efficacy of MRI and mammography for breast-cāncer screening in women with a familial or genetic predisposition. N Engl J Med. 2004;351:427-437.) There is also an article review on breast cancer screening (can't remember the ref) but they say that MRI is not for screening, it is for diagnosis in cases of high risk for breast cancer, or when mammography is not sufficient. Besides, the MRI has a lower sensitivity when compared to mammography, And worst, 402 additional procedures and 207 aditional biopsies were performed in a series of patients with abnormal MRI, when only 24 and 7 were respectively performed with mammography.
-- Ricardo Savaris, MD Porto Alegre - Brasil
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