Re: Tamoxifem & Mirena

From: Atkinson, Samuel M (ATKINSONS@mail.ecu.edu)
Fri Oct 28 12:13:55 2005


Endometrial cancer is reported with long term Tamox but I have done many biopsies for the increaded endometriums on Tamox and they are invariably neg. At D&C there is no endometrium at all. I think, but obv cannot prove that Tamox causes an US pix of thickened endomet that is really a fibrosed thickened myometrium that gives a false positive report. Thus I now stop with a negative Pipelle. Certainly agree with the Mirena unless you know she is PM for sure (like an FSH). Pf course 1.12 is not excessive for a menstruating woman!.

-----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Joanne Bulley, MD Sent: Thursday, October 27, 2005 5:19 PM To: Multiple recipients of list OB-GYN-L Subject: Tamoxifem & Mirena

50yo G2P2 Breast CA 2000 (because I insisted she have her mammograms in '99 & '00 - she tried to argue her way out).

Treated with excision / sentinel nodes and radiation therapy. Followed by 5 years Tamoxifen which was completed 9/00.

Mirena placed for contraception 08/04.

Erratic bleeding during the summer.

US done (because of Tamoxifen even though most likely benign peri-menopausal bleed with Progesterone IUD)

US IUD in place. Some fibroid change. Endometrium 1.12 cm. Ovaries Fine.

Thoughts, anyone?

--
Joanne Bulley, MD
Keene, NH, USA

"Love is indescribable and unconditional. I could tell you a thousand things that it is not, but not one that it is." - Duke Ellington, American jazz artist (1899-1974).





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