Re: Termination of pregnancy with Hemabate

From: Robert J. Carpenter, Jr. MD (zygote@icsi.net)
Tue Oct 11 16:49:20 2005


You need to read the original Scandanavian literature. In Houston for 15 years before Cytotec, Hemabate was used intramnitoically. It was the first derivative from the original f2a that was synthesized. More stable, less required. Used by the Swedes for IA terinations. The literature is buried in the Upjohn files. The reason it was not marketed was that f2a was being marketed and they did not want to have competing drugs. Hemabate is superior.

Best recal is 1978-1980 articles - donot remember which J.

Bob

On 11 Oct 2005 at 11:06, Andrew Folley wrote:

> I have never heard of using hemabate for this indication. Typically
> it would be prostaglandin suppository,, high dose pitocin etc.
> Theoretically hemabate should work as it is a prostaglandin. The
> question is what dose and how long andy
>
> >From: dmecnm@aol.com
> >Reply-To: ob-gyn-l@obgyn.net
> >To: Multiple recipients of list OB-GYN-L <ob-gyn-l@dns.obgyn.net>
> >Subject: Termination of pregnancy with Hemabate Date: Tue, 11 Oct
> >2005 10:18:03 -0500
> >
> >Question came up in resident sign outs today. Any information would
> >be greatly appreciated.
> >
> >G2P1001
> >22 weeks gestation with multiple anomalies.
> >Admitted for termination of pregnancy.
> >Cervix long and closed.
> >Cytotec, multiple doses, given over the last 24 hours, with no change
> >in cervix. Attending has ordered hemabate be given. We do not have a
> >policy regarding hemabate in this situation.
> >
> >Anyone have any information? Protocols? Anecdotal stories?
> >
> >Thanks,
> >Denise, CNM
> >So Cal
> >
>

--
Robert J. Carpenter, Jr. MD
6624 Fannin, #2720
St. Luke's Medical Tower
Houston,TX 77030-2339
713-795-4600




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