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Re: glucosamine and pregnancy From: ainsron (ainsron@sbcglobal.net) Wed Aug 31 20:55:10 2005 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Charlie Chambers: "whiteners and pregnancy" Previous message: Larry Glazerman: "Re: GYN: RV fistula" In reply to: Len2976@aol.com: "glucosamine and pregnancy" According to the website of one of the manufacturers: Question: Is Nn Glucosamine safe to take during pregnancy or whilst breastfeeding? Answer: No study so far has been dine with glucosamine in regards to pregnancy and breastfeeding. We therefore advise that you do not take glucosamine during pregnancy or whilst breastfeeding. On the other hand, glucosamine is a natural substance found in the body and empirically, I would say it poses very little risk in pregnancy. On the other hand, why have a patient take any chemical that has no proven benefit in treatment of arthritis, it is used because snake oil salesmen ran out of snake oil. A randomized, double-blind, placebo-controlled trial of glucosamine sulphate as an analgesic in osteoarthritis of the knee R. Hughes and A. Carr1 St Peter's Hospital, Chertsey, Surrey and 1 University of Nottingham, Nottingham, UK Objectives. A randomized, placebo-controlled, double-blind trial of the relative effectiveness of glucosamine sulphate and placebo in managing pain in osteoarthritis (OA) of the knee. Methods. Eighty patients with OA of the knee were recruited from a rheumatology out-patient clinic and received either glucosamine sulphate 1500 mg daily for 6 months or dummy placebo. The primary outcome measure was patients' global assessment of pain in the affected knee. Results. Area under the curve analysis for the primary outcome measure showed no difference between placebo and glucosamine [mean difference 0.15 mm, 95% confidence interval (CI) -8.78 to 9.07]. The placebo response was 33%. There was a statistically significant difference between groups in knee flexion (mean difference 13°, 95% CI -23.13 to -1.97), but this difference was small and could have been due to measurement error. Conclusions. As a symptom modifier in OA patients with a wide range of pain severities, glucosamine sulphate was no more effective than placebo. Ronald E. Ainsworth, MD, FACOG -----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Len2976@aol.com Sent: Tuesday, August 30, 2005 5:04 PM To: Multiple recipients of list OB-GYN-L Subject: glucosamine and pregnancy We have a new OB patient (6 wks getation) who has a past history of osteomylitis in her hip with resultant DJD. She has been taking glucosamine for a while, feels it has been helpful, and has asked for information on its use in pregnancy. Does anyone have any knowledge on its use in pregnancy? Lenora McCall, CNM Next message: Charlie Chambers: "whiteners and pregnancy" Previous message: Larry Glazerman: "Re: GYN: RV fistula" In reply to: Len2976@aol.com: "glucosamine and pregnancy"

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