Re: Breast Cancer and HRT

From: Joanne Bulley, MD (islesannie@yahoo.com)
Tue Aug 9 21:44:36 2005


I recall that in the WHI even though they talked about an increase risk of breast cancer with combined PremPro -- they stated that family history of breast cancer did not make that any different than no family history. That is, no further "increase". One aspect that has been steadily overlooked is that even though the numbers look like a 26% (I think -- I am at home without the articles) increased risk, even that was not statistically significant. It has still been repeated so often (that the continuous combined Prempro increases the risk) - it is like a mantra - it has been said so often it is now taken as fact.

So ... with this patient - I would present the data as I have reviewed it and as it has been reviewed at various conferences I have attended, reviwe the fact that if she consults with any of the oncologists or surgeons (at least in this area) they will universally tell her to stop HRT immediately. Then the patient gets to make the decision.

I have told many a woman that if she is anxious about all the info on both sides of the HT issues everytime she goes to take the HT, then she should not be on it - the anxiety is not good for her.

Joanne

At Tue, 09 Aug 2005, Lois wrote: >
>I have a 40 year old premature menopausal patient (4years) who is on
>HRT because of debilitating hot flushes. She is on ethinyl estradiol and
>prometrium daily for 4 years and her hot flushes have disappeared. Her
>49 year old premenopausal sister has recently been diagnosed with breast
>cancer. There is no family history of breast, ovarian or colon cancer.
>Should we stop the HRT/ What is her risk of breast cancer with and
>without the HRT?
>
>Geoffrey Kalchman
>Mt Sinai Hospital
>Toronto ON

--
Joanne Bulley, MD
Keene, NH, USA

"Love is indescribable and unconditional. I could tell you a thousand things that it is not, but not one that it is." — Duke Ellington, American jazz artist (1899-1974).





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