Re: Gestational pruritus in 3rd trimester and intrauterine fetal

From: Peter Wein (pwein@unimelb.edu.au)
Sun Aug 7 03:42:59 2005


Ursodeoxycholic acid much better - there has been RCT showing improved outcome in IHCP with urso, much better tolerated.

--
Peter Wein

art fougner, md wrote:

>Cholestyramine resin may be useful in this situation. > >art > >At Thu, 04 Aug 2005, Robert J. Carpenter, Jr. MD wrote: > >>The data concerning cholestasis and pruritis gravidarum is a complex bag. The >>original separation was the presence of pruritis only without abnormality of lifer >>funcrttions tests (LFT). That has a low probability of IUFD but it does occur. The real >>question is what degree compared to the background of normal patients. With >>elevated LFT then the IUFD rate increases and surveillance is indicated. The >>Europeans use an agent but name not in head at this moment. Best recall study >>about 24 months ago from either Sweden or Norway. Go to PubMed and search will >>pull up the article. >> >>I use fetal mvement counts as per the method of Eliah Sadovsky as my prime >>surveillance tool. Mom counts for 30 mninutes TID at same time of day and about >>90-120 minutes post meal. After 4 days of counts the average is taken and that is the >>"truth" If there is a decrease by 50% on 2 consecutive counts then other testing >>usually CST is done. Mom's appreciation of movem,ent is your best index of well >>being. >> >>If severe pruritis is present at 30 weeks then some surveillance is indicated as Dan >>indicated. >> >>On 4 Aug 2005 at 21:27, R. Daniel Braun wrote: >> >>>There are other papers back before that one which say the same thing. >>>We start fetal surveillane at 30 weeks and deliver at 35 weeks in our >>>patients with Chlestasis of pregnancy. Dan >>> >>> On 8/4/05, Ricardo Savaris <rsavaris@hcpa.ufrgs.br> wrote: >>> >>>>Dear all, >>>> >>>>I am a little bit away from the obstetrics front , but I received an >>>>information about the gestational pruritus in 3rd trimester and >>>>intrauterine fetal demise. What I found was a series of cases (BJOG, >>>>2004,Jul;111(7):676-81.) and I don't have access. Nevertheless, it >>>>doesn't seem to a good evidence. If you give me some literature to >>>>read would be interesting, but your personal experience would be >>>>even better. >>>> >>>>Ricardo Savaris >>>> >>>-- >>>R. Daniel Braun >>>Kinky for Governor >>> >>-- >>Robert J. Carpenter, Jr. MD >>6624 Fannin, #2720 >>St. Luke's Medical Tower >>Houston,TX 77030-2339 >>713-795-4600 >> > >-- >art fougner, md > > "If you don't know where you are going, you will wind up somewhere else." >Lawrence Peter Berra >





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