Re: Fibroids/endometriosis/adenomyosis

From: Elrod Darryl G MAJ 48 MDOS/SGOBO (Darryl.elrod@LAKENHEATH.AF.MIL)
Thu Apr 7 02:23:34 2005


I'd have to agree. I've used Aygestin with most women I put on Lupron with good resolution of the hotflushes.

Why does she or would she want to keep her uterus?

Glen

-----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Larry Glazerman Sent: Thursday, April 07, 2005 3:18 AM To: Multiple recipients of list OB-GYN-L Subject: Re: Fibroids/endometriosis/adenomyosis

Whenever I use Lupron, I add Aygestin, 5 mg daily, as per the extensive data published by Eric Surrey. I don't think there's any significant DVT risk. I also think, however, I'd offer hysterectomy, since the Lupron isn't often a long term cure.

Larry R. Glazerman, MD Ob-Gyn at Trexlertown, PC 610-402-0161 l.glazerman@rcn.com

> -----Original Message-----
> From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of
Garry E. > Siegel, M.D.
> Sent: Wednesday, April 06, 2005 9:38 PM
> To: Multiple recipients of list OB-GYN-L
> Subject: Gyn: Fibroids/endometriosis/adenomyosis
>
> 49 YO P2102 with:
>
> known fibroids--4 cm intramural/subserosal one seen at lapscope a few
> years ago, still seen on scan and felt on exam
>
> Stage 2 endometriosis from same lapscope, excised totally
>
> S/P endometrial ablation for menorrhagia, done concurrently with
> lapscope. No fibroids in the cavity
>
> Also germane is that she has had a LEEP subsequent to the above for
CIN2 > (clear margins) with adenomyosis.
>
> Lastly, in college, she had a traumatic DVT and never has been on the
> pill.
>
> She was seen in December with worsening menometrorrhagia and pelvic
> pain, and placed on Lupron. She has become amenorrheic, has no pain,
> and says her abdomen is smaller (clinically she is around 8 weeks size
> today, no real change).
>
> She is very troubled by hot flashes.
>
> Options I've kicked around:
>
> 1. Increasing her Zoloft dose (already on 100 mg/day).
> 2. Adding a progestin (which one? dose?).
> 3. Add low dose combination estrogen/progestin therapy (remember the
> DVT); if this is considered, might thrombophilia testing be in order?
> 4. Of course, LAVH-BSO, but for the sake of discussion, let's stick
to > non-surgical options for now.
>
> Garry
>
> --
> Garry E. Siegel, M.D.
> Private Practice
> Roswell, GA





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