Re: hyperplasia and endometrial ablation

From: Larry Glazerman (l.glazerman@rcn.com)
Sat Nov 27 20:07:32 2004


I've done a lot of ablations, and taught ablation at numerous postgraduate courses. I have mixed feelings on this issue. Initially, when ablation was first developed (anyone remember the Nd:YAG laser?), ANY hyperplasia was considered a contraindication. This was because of the presumption that ablation would cause an Asherman's syndrome, and a possible carcinoma that developed might not be detected if it were in a "loculated" island of endometrium. The fact is that ablation generally does NOT cause an Ashermans.

In addition, many believe that simple, non-atypical hyperplasia is a totally different bird than complex atypical hyperplasia, and that the former has virtually no risk of malignant transformation. I might judiciously ablate someone with simple hyperplasia, but I'd probably choose a resection.

_____

From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of RModugno@aol.com Sent: Saturday, November 27, 2004 6:53 PM To: Multiple recipients of list OB-GYN-L Subject: Re: hyperplasia and endometrial ablation

In a message dated 11/18/2004 6:07:30 PM Eastern Standard Time, johnprov@sympatico.ca writes:

If she had true endometrial hyperplasia then there is a good chance the abalation will fail. I would put here on provera 10 mg Q daily X 3 months and then just do on office sampling. The sample should show atrophic or sectretory endodometrium. If atrophic I would just tell her to return for future sampling with and irregular bleeding. If secretory I would tell her the hyperplasia is gone but the abalation will most likely not stop her menses though hopefully they will be lighter.

--
                                 Take care, John

John - do you have any evidence that simple hyperplasia without atypia will not respond to endometrial ablation?

Robert Modugno MD MBA FACOG

marietta, GA

http://www.novaobgyn.yourmd.com





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