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Re: Estrogen and breast cancer From: Joanne Bulley, MD (islesannie@yahoo.com) Thu Jul 29 08:10:45 2004 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Joanne Bulley, MD: "Re: Anyone doing saliva hormone levels? Bio-identical hormone treatment?" Previous message: art fougner, md: "OB: Appendicitis In Pregnancy" In reply to: art fougner, md: "Re: Estrogen and breast cancer" Next in thread: Terrence.Jones@kp.org: "Re: Estrogen and breast cancer" I am convinced that for the majority of us (women) who will get breast cancer -- will get it ... period. There is a lot of evidence (partidularly now the estrogen only arm of the WHI) that indicates it is not the estrogen that induces the cell to become cancer. I am also convinced that the function of the SERMs - Tamoxifen and Raloxifene - on reducing estrogen receptor positive breast cancers - is one of delaying not preventing ever getting it. But there is no data for that - so that is not what I tell my patients. It is my opinion - not fact - that we live long enough that some of these things just happen. Look at the prostate cancer data. It appears that if men live long enough about 75% will eventually get it. Do we know yet if that is testosterone exposure - and what man would go wihthout his testosterone until he already has prostate cancer? I know men who quit their Lupron or whatever the other GnRH drug is - they'd rather let the cancer have its way than not have sex! We are still looking for the cause of these age related diseases and illnesses. I think estrogen probably helps breast cancer be less aggressive (like Dan Braun commented) and if it helps the general wel beeing be better for someone - then go for it. If I have a patient that is convinced she will stay on estrogen no matter what - then I let her know my philosphy and let her know that it is not any sort of scientific data but philosphy and I will support her in her decision. But I no longer tell women that they should definitely plan on estrogen. I tell them some info - tell them to gather their own information and ask question of me whenever needed and we will cross that bridge with whatever data is available at the time of need. Whew! I got a bit long winded there! Joanne At Wed, 28 Jul 2004, art fougner, md wrote: > >Another factor is genetic predisposition. Since none of these studies >report BRCA status, legitimate questions remain. > >art > >At Wed, 28 Jul 2004, Braun, R. Daniel wrote: >> >>Actually, does not the same issue apply to Estrogen Replacement Therapy >>and endometrial carcinoma? All those who got endometrial CA while on ERT >>had stage I Grade I lesions. >> >>Dan >> >>"Sound is like water. If you drill one hole in the wall the sound will >>leak right through." >> >>- JAY BRAUN, a band member by love, a soundproofer by necessity. -- Joanne Bulley, MD Keene, NH, USA Next message: Joanne Bulley, MD: "Re: Anyone doing saliva hormone levels? Bio-identical hormone treatment?" Previous message: art fougner, md: "OB: Appendicitis In Pregnancy" In reply to: art fougner, md: "Re: Estrogen and breast cancer" Next in thread: Terrence.Jones@kp.org: "Re: Estrogen and breast cancer"

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