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Re: COX 2 inhibitors in pregnancy From: Richard Chudacoff, MD (dean@thehuffpeople.net) Wed Jul 28 13:27:08 2004 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: art fougner, md: "Re: COX 2 inhibitors in pregnancy" Previous message: Richard Chudacoff, MD: "Re: COX 2 inhibitors in pregnancy" In reply to: Lynn D. Montgomery, M.D.: "Re: COX 2 inhibitors in pregnancy" Next in thread: Len2976@aol.com: "Re: COX 2 inhibitors in pregnancy" .. There is a recent article in Fertility & Sterility on the topic. It is only two pages long. If you want to see a copy, contact me privately. It was one of the articles for the July ABOG mailing in General OB/GYN for Board recertification. Fertil Steril. 2004 Mar;81(3):493-4. The potential danger of COX-2 inhibitors. Norman RJ, Wu R. Department of Obstetrics and Gynecology, The University of Adelaide, The Queen Elizabeth Hospital, Woodville, South Australia, Australia. robert.norman@adelaide.edu.au Cyclooxygenase (COX)-2 inhibitors have a major effect on ovulation and may impair fertilization, decidualization, implantation, and parturition, as well as female fertility. Women attempting to become pregnant need to pay more attention to their use of COX-2 inhibitors. PMID: 15037388 - - - - Quoting "Lynn D. Montgomery, M.D." <apgar10@montanadsl.net>: > Even though there were hopes that the COX 2 meds would not have the same > effects of ductal closure, decreased amniotic fluid volume, possible > fetal bowel and kidney issues as the earlier COX 1& 2 non-steroidals, it > appears they have the same potential for fetal risk. As such, they can > be used only for a limited time (72 hours period) between 24 and 32 > weeks for indications such as preterm labor or degenerating fibroids. > Lynn > > Lynn D. Montgomery, M.D. > Maternal-Fetal Medicine, OB/GYN > Rocky Mountain Women's Health > 2835 Fort Missoula Rd., Suite 303 > Missoula, Montana, 59804 > 406-549-0978 > fax 406-549-0987 > e-mail: apgar10@montanadsl.net > -----Original Message----- > From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of > Richard Chudacoff, MD > Sent: Tuesday, July 27, 2004 4:40 PM > To: Multiple recipients of list OB-GYN-L > Subject: COX 2 inhibitors in pregnancy > > Anyone have info on using Bextra or Celebrex in pregnancy for uterine > irritability, probably caused by adenomyosis or serosal endometriosis? > > Richard Chudacoff, MD, FACOG > > Chudacoff Obstetrics & Gynecology, PA > > 15200 Southwest Freeway, #270 > > Sugar Land, TX 77478 > > Tel: 281-277-3900 > > Fax: 281-277-3901 > > rchudacoff@mylinuxisp.com > > Richard.Chudacoff@obgyn.net > > http://www.mdhub.com/281-277-3900 > > http://www.chudacoffobgyn.yourmd.com > > *****HIPAA Confidentiality Notice***** > > The documents inside this electronic transmission contain confidential > information belonging to the sender that is legally privileged. This > information is intended only for the use of the individual or entity > named above. The authorized recipient of this information is prohibited > from disclosing this information to any other party and is required to > destroy the information after its stated need has been fulfilled, unless > otherwise required by law. > > If you are not the intended recipient, you are hereby notified that any > disclosure, copying, distribution, or action taken in reliance on the > contents of these documents is strictly prohibited. If you received > this electronic transmission in error, please notify the sender > immediately to arrange for return. > Next message: art fougner, md: "Re: COX 2 inhibitors in pregnancy" Previous message: Richard Chudacoff, MD: "Re: COX 2 inhibitors in pregnancy" In reply to: Lynn D. Montgomery, M.D.: "Re: COX 2 inhibitors in pregnancy" Next in thread: Len2976@aol.com: "Re: COX 2 inhibitors in pregnancy"

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