ENDO Messages for July, 2009: Re: High CA 125 after partial hysterectomy and endometriosis

Re: High CA 125 after partial hysterectomy and endometriosis

From: E. (anonymous@obgyn.net)
Thu Jul 30 18:48:32 2009

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The C125 test has a high false positive rate. I think you're doing the right thing in terms of having the test repeatedly, this can show whether the level rises over time, and can indicate a potential problem.

However, the test can come up positive for adenomyosis (endo of the uterus), endometriosis, ovarian cysts, PID, fibroids and pregnancy, so there could be any of those things going on.

I would ask the doctor what she thinks and then ask her if she would test you again in 3 more months.

If the level is still high, maybe you should ask about another lap exploration or seek another opinion with another doctor.

I picked up the following information from a website: http://www.ovariancancer.jhmi.edu/ca125qa.cfm

>>However several women's reproductive disorders can cause a false positive result. Endometriosis, benign ovarian cysts, first trimester of pregnancy, and pelvic inflammatory disease all produce higher levels of CA-125.

70% of people with cirrhosis, 60% of people with pancreatic cancer, and 20%-25% of people with other malignancies have elevated levels of CA-12 , Colleen wrote: >
>Hello
>This is my first posting. I have had a consistently high CA 125 for
>about a year and a half. My first reading was 200. I had several tests
>- CT of abdomen, internal ultrasound, etc. Found I had a small fibroid
>- waited it out a year and had another CA125 - reading of 100 -also had
>lots of abdominal pain and bloating,etc during that year. OB/GYN
>suggested laproscopic evaluation to see if I had endo., and we decided
>to be conservative if findings allowed so as not to put me in surgical
>menopause. When she went in my left ovary and fallopian tube were full
>of endometrosis. Everything else looked great. She removed left ovary
>and tube and fibroids - biopsied fibroids -came back fine. 2 months
>later I asked for a repeat CA125 just for piece of mind. It came back
>189. Wondering if anyone has had this situation. I was thinking the
>reading would be mormal or close to normal (under 35) since she removed
>all of the endo... Any ideas?
>

Next message: Rebecca: "Re: Mirena experiences? Cramping after insertion?"
Previous message: Colleen: "High CA 125 after partial hysterectomy and endometriosis"
Maybe in reply to: Colleen: "High CA 125 after partial hysterectomy and endometriosis"

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