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Re: ENDOCERVICITIS AND ADENOCARCINOMA

From: anna (anonymous@obgyn.net)
Wed Aug 29 23:41:20 2007


At Sat, 2 Mar 2002, Leena wrote: >
>Hello Doctor,
>
>My friend was recently diagnosed with adenocarcinoma endometrium. She
>is a newly wed who is only 31 years old and has no kids yet. For many
>years she was suffering with heavy bleeding and severe pain during her
>period. Recently her gynacologist did a D&C on her and when the results
>came she was diagnosed with adenocarcinoma endometrium cancer. The
>final pathologist's report says "The Specimen sent as 'EA' shows
>features of well differentiated adenocarcinoma with squamous metaplasia
>and foci of atypical hyperplasia. 'ECC' shows Chronic endocervicitis."
>Her cancer is in Stage I.
>
>A group of Gynacologists that is currently treating her suggested that
>since she is young they are going to take a chance for a month by
>treating her with reverse hormonal therapy with Provera
>(Medroxyprogesterone acetate) 10mg to be taken 3 times a day. After a
>month they are going to do another biopsy on her to see whether the
>cancer cells have shrunk. If not, they will be doing a total abdominal
>hysterectomy (uterus, ovaries, and fallopian tubes to be removed).
>
>My questions are as follows:
>
>1. Even if this particular treatment appears to respond by shrinking
>the cancer cells and thus they decide not to do the hysterectomy right
>away, won't she have to keep taking the Provera? She and her husband
>would like to try for a baby before they do the hysterectomy but I
>recently read in an article that Provera is a contraceptive and if that
>is true won't there be a problem for her to conceive? Will that be too
>much of a risk for her to wait at least a year to have a baby or is it
>safer for her to immediately remove the uterus due to the adenocarcinoma
>endometrium?
>
>2.The report also shows that she has chronic endocervicitis, was this
>caused by the adenocarcinoma or was there another cause such as STD?
>Does she need to be treated specifically for this? Does her husband need
>treatment for this too since I read somewhere that this is contagious
>and if left untreated it might cause other complications? If
>endocervicitis was not caused by STD, and is caused by adenocarcinoma
>then does that mean that this was still caused by the same bacteria
>(chlamydia trachomatis)? If so then does she and her husband still need
>treatment for this?
>
>Kindly provide me with your valuable opinion and suggestions with
>regards to this matter.
>
>Thanks and I greatly appreciate your advise and help.
>
>--
>Leena
>



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