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Re: Does any one know what to do about this?

From: Amy (anonymous@obgyn.net)
Tue Dec 12 08:04:09 2006


Marie,

I have been reading a lot of your posts on the forum and just wanted to say hang in there. I cannot imagine trying to deal with something as awful as endo while stationed in the military in a foreign country. I hope the forum is at least providing some comfort to you.

I also wanted to comment on your Lupron experience: I have done it twice, both times very successfully and luckily with few side effects or problems. I had mood swings too but found them to be at their worst when I was first starting the treatment. My doctor told me that initially the ovaries get confused with the Lupron and produce a SURGE of estrogen before they figure out they are supposed to STOP producing it. Because of this surge, your initial symptoms can worsen before they taper off. This was definitely true for me. The first month was the worst but I had made a promise to myself to stick it out for at least three months (again, Doc told me it could take that long for my body to adjust to chemical menopause) before I made a decision. For me, the mood swings did get better and the pain decreased completely. I did still have hot flashes and night sweats, and an occasional mood swing ubt nothing as bad as the first month. I handled Lupron well enough to do it again a few years later and would consider it a third time if need be.

As far as anti-depressants: I starting taking anti-depressants about 4 years ago (depression and anxiety run in my family.) When I started my second course of Lupron, my OB/Gyn recommended I stop taking the anti-depressants (Lexapro) because it coupled with Lupron could make depression worse. I do not know if that is with all anti-depressants or even how much truth that holds. (I haven't found any real research but must also confess I haven't looked really hard either.) But I trusted my doctor (still see him today-have a PAP this afternoon as a matter of fact) and did not want to take chances so I tapered off the Lexapro before the Lupron started and then went back on it (still take it today) after my shots were finished. All of this was done of course, with the consultation of my family doctor, who had prescribed the Lexapro. Anytime you take anti-depressants though, it can be a rough road. It may take trying several kinds before you find the right one for you and it can take 4-6 weeks before the effects are really felt. I am lucky that Lexapro was the first I tried and it works well for me, but the first 4 weeks of starting it were rough-lots of side effects and MAJOR mood swings, all of which disappeared after my body adjusted to the meds.

Hope this helps a little! Feel free to email me direct if you want to talk off line. I hope you are feeling better today. Hang in there! I will keep you in my thoughts and prayers.

Hugs!Amy Meyer

At Wed, 6 Dec 2006, Marie wrote: >
>I am taking Lupron right now. I am up for my second shot next week. I
>am still having pain, not excuciating like normal, but enough to make me
>miserable. Nothing except percocet seems to have touched the pain at
>all. The part I need the post help with is, I think the lupron is
>making me have mood swings. I cry for no reason at all, and the
>smallest things seem huge to me. I get mad easily. It is really
>hurting my long term relationship with my boyfriend. (who has been with
>me since the endo started) Has any one else on lupron experienced this?
>What helped? Should I just try a Anti-depressant? The only problem if I
>should use an anti-depressant is that it will effect my job. I can not
>Physically DO my job if I am on anti-depressants. Please help me...




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