Re: Asoprisnil
From: Jean (anonymous@obgyn.net)
Sat Jul 31 05:39:53 2004
Hi Anne,
Thanks for the information -- I may be in menopause before it ever gets
approved for endo, LOL!
--
Jean
At Fri, 30 Jul 2004, Anne wrote:
>
>At Thu, 3 Jun 2004, Jean wrote:
>>
>>Has anyone been able to try Asoprisnil (a selective progesterone
>>receptor modulator) for endo or fibroids? I think it may still only be
>>available in clinical trials. I've heard that it usually stops your
>>period while you're on it, with minimal side effects? I'd be interested
>>to hear about anyone's experience with it.
>>
>>--
>>Jean
>>
>Jean,
>I too have been very excited about this promising investigative drug. So
>far it has has tested better than RU-486 in that it does not cause
>overgrowth of the endometruim and androgenic side effect. It also does
>not cause loss of bone density like Lupron (also TAP's drug), so can be
>taken long-term. It is in phase II trails for endo and phase III for
>fibroids.
>I have fibroids but already am symptomatic with inability to urinate if
>I let my bladder get too full, so, if my fibroids continue to grow I
>don't know if I can avoid surgery before this drug is approved.
>
>According to TAP labs it will be submitted to the FDA for approval in
>2005, so expect it to be approved by the end of 2006 for fibroid
>treatment. Endo approval would probably be about a year later.
>
>If you can hang in there a few more years you might try this then.
>
>I would really like to hear from women who have been involved in the
>clinical trials what their experiences with any side effects were/are,
>since that is why I am basically scared to death of Lupron and looking
>for the next best drug therapy.
>
>To the doctors- what is the buzz on this drug in your circles?
>
>--
>Anne
>
--
Jean
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