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Re: A few questions for AudreyFrom: AGS (anonymous@obgyn.net)Mon Mar 31 01:03:08 2003
There have been reports that women with endometriosis have elevated levels of Interleukin(IL)-1beta, which stimulates vascular growth. This would be similar to varicose veins only in the pelvis, and could certainly lead to the "pelvic congestion syndrome" that you had. There was a conference in April 2002, reported in Medscape, (I have a professional subscription -- not a doctor, though!) that summarized some of these findings. The info on the classifications of endo came from an OB-GYN listserv for professionals where some gynecologists have written expressing their interest and wondering how these things get classified. The final answer is that it is NOT classifiable as a neoplasm, and in this moment I cannot remember the final reason, but a passionate argument was raised in favor of endo's inclusion in that class of disorders. There has also been some recent research on endo and its links to auto-immune disorders...there are not good explanations for why many women (up to 80% by some reports) have endometrial implants, but only a small percentage of us develop the biochemically active endometriosis. It may be that there are those of us prone to over-active inflammatory responses who experience such grief at the mercy of this disorder. Hope this helps! I've researched the subject rather thoroughly...at one time I was considering submitting an article to "Redbook" about the subject. If you can get the NY Times on-line (I believe registration is free), Jane Brody wrote an article on the subject a couple of months ago... Audrey
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