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Re: blood transfusion/breast trauma lead to breast cancer?

From: Kathleen (anonymous@obgyn.net)
Wed, 14 Mar 2001 17:52:13 -0600 (CST)


Dear Dr. Brooks:

Thank you so much for returning my note about my concerns about blood transfusions and/or breast trauma leading to breast cancers. I can see what you mean about the blood supply, though, because the blood that was in my breast due to the bruising was terrible. And, like I stated before, it took over a month to heal. Anyway, you wanted to know where I received the reference about the blood transfusions? It was on OncoLink. Main Menu was Cancer FAQs. I think this is the site: http://www.oncolink.upenn.edu/causeprevent/faq/bloodtrans. It sites the two articles that I referred to in my March 12th letter. I can not access the original articles from JAMA OR NEJM as I am not a physician. It never stated the dates of the articles. I am sure that I would find the articles fascinating, if I was allowed on that site. I am sure you will be allowed access as you will have a Physician's ID number. Thanks again for your help!

At Tue, 13 Mar 2001, Hannah wrote: >
>Dear Kathleen-
>There are very rare reported cases of cancer after trauma;they are
>usually related to burn scars evolving into skin cancers later in
>life. More than likely, the episodes of blood transfusions and the
>diagnoses of cancer in you and your mother were coincidences. What
>CAN sometimes happen is that a tumor,which is more vascular (has more
>blood vessels) than the surrounding tissue,is growing quietly UNTIL a
>trauma to the area causes a bleed. So, in your case, it may be
>fortunate that the accident caused a bleed that called attention to
>the small tumor in the area. Please include the references from the
>JAMA and NEJM articles you are citing. It would be interesting to
>read the information. Thank you.
>Hannah Brooks, MD, FACS
>
>Date: 03/12/2001 06:53pm
>
>I was in a major car accident in 1999, at the age of 42. I needed
>surgery, which required my accepting 3 ccs of plasma. I also had
>major
>breast trauma from the seat belt, which took over a month to heal.
>Seven
>months later, I had a routine mammogram, which showed a solid mass.
>Two
>weeks later, I was diagnosed with a very small cancer. Had a
>lumpectomy
>for the -1/4" tumor. Has this happened to anyone else? Do you think a
>breast trauma can lead to a cancer? I know that the stress can
>accelerate the tumor cells that everyone has in their body, but can a
>direct trauma do it, too? Also, there was an article in the JAMA and
>NEJM that two different surgeons contacted a cancer via a cut on their
>hands while performing an operation on a patient who later was
>diagnosed
>with a cancer? So, does this mean that blood transfusions can possibly
>be blamed for some cancers? That's what the JAMA is wondering. I am
>curious to know if either of these two possibilities has happened to
>other recently-diagnosed breast cancer patients. Incidentally, in
>December of 1999, my mother had major surgery, which required blood
>transfusions. Three months later during a routine mammo she, too, was
>diagnosed with breast cancer. Weird, right? So, please write to me at
>anonymous@obgyn.net Thanks


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